neural activity. Deficiency can result in beriberi and is a factor in alcoholic neuritis and Wernicke-Korsakoff syndrome; Thiamine Hydrochloride can be used to treat Vitamin B1 deficiency. With the

development of clinical pharmacology in recent years, Vitamin B1 is found to be helpful in treating

many other diseases. It is an essential ingredient for compound feed, and it may facilitate growth

of young animals. It is also used a nutritional supplement in sports drinks.

Quality standard:

Items		Standard	Result
BP2012	Appearance	White or almost white, crystalline powder or colourless crystals	White crystalline powder
	PH	2.7-3.3	3.1
	Water	≤5.0%	2.25%
	Sulphated ash	≤0.1%	0.01%
	Sulphates	≤300ppm	<300ppm
	Heavy metals	≤20ppm	<20ppm
	Related substances
	—Any impurity	≤0.4%	<0.05%
	—Total impurities	≤1.0%	<0.05%
	Assay	98.5-101.0%	99.7%
USP36	Identification	A: IR absorption; B: Tests of Chloride	Comply
	Absorbance of solution	≤0.025%	0.017
	Limit of nitrate	No brown ring produced at the junction of the two layers	Comply
	PH	2.7-3.4	3.2
	Water	≤5.0%	2.34%
	Residue on ignition	≤0.2%	0.01%
	Chromatographic purity	≤1.0%	0.23%
	Residual solvent
	—Methanol	≤0.3%	0.05%
	—Ethanol	≤0.5%	<0.01%
	Assay	98.0-102.0%	99.6%
Conclusions		This batches complies with the specification of BP2012 and USP36

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